Efficiency of Transmission of Microorganisms From Mother to Fetus
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The efficiency of transmission from the infected, immunocompetent mother to the fetus varies among microbial agents and also can vary with the trimester of pregnancy. Primary infection, whereas in utero transmission of cytomegalovirus (CMV), HIV, and T. pallidum can occur in consecutive pregnancies. The risk of congenital rubella infection in fetuses of mothers with symptomatic rubella was high in the first trimester (90% before 11 weeks of gestation), declined to a low of 25% at 23 to 26 weeks, and then rose to 67% after 31 weeks. Infection in the first 11 weeks of gestation was uniformly teratogenic, whereas no birth defects occurred in infants infected after 16
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Article Title: Efficiency of Transmission of Microorganisms From Mother to Fetus
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